List Of Narcotics By Class

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HIV infection starts when the virus is transmitted through contact with infected body fluids, such as blood, semen, or breast milk. HIV targets the immune system and invades white blood cells called T-cells. These are cells that fight infection. By entering the body’s cells, the virus hides from the immune system.

After the virus invades these cells, it replicates (makes copies of itself). Then, the cells explode. They release many viral cells that go on to invade other cells in the body. This process destroys the immune system’s ability to fight infections, and generally keeps the body from working well.

Currently, there is no known cure for HIV. However, medications can help people living with HIV manage the condition and live healthy lives. These drugs work by stopping HIV from replicating. Here is a list of drugs that are currently approved by the U.S. Food and Drug Administration (FDA) to treat HIV.

There are many different classes of drugs used to treat HIV. Each person’s doctor will decide on the best medications for them individually. This decision will depend on their viral load and strain, as well as on how severe their case is and how far it has spread.

All people with HIV need to take more than one drug. This is because attacking HIV from multiple directions reduces the viral load more quickly. It also helps prevent resistance to the drugs being used. This means a person’s medications may work better to treat their HIV.

Combination drugs combine medications from different classes into one drug form. The drugs are combined to make a complete HIV regimen. This type of regimen is usually used to treat people who have never taken HIV medications before.

Examples of these drugs include:

  • abacavir/dolutegravir/lamivudine (Triumeq)
  • dolutegravir/rilpivirine (Juluca)
  • elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate (Stribild)
  • elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (Genvoya)
  • efavirenz/emtricitabine/tenofovir disoproxil fumarate (Atripla)
  • emtricitabine/rilpivirine/tenofovir disoproxil fumarate (Complera)
  • emtricitabine/rilpivirine/tenofovir alafenamide (Odefsey)
  • bictegravir, emtricitabine, and tenofovir alafenamide (Biktarvy)

Integrase inhibitors are a class of medication that stops the action of integrase enzyme. This is a viral enzyme that HIV uses to infect T-cells. Integrase inhibitors are usually among the first HIV drugs used in people who have recently contracted HIV because they work well and have minimal side effects. Examples of these drugs include:

  • dolutegravir (Tivicay)
  • elvitegravir (Vitekta)
  • raltegravir (Isentress)
  • raltegravir extended-release (Isentress HD)

Several combinations of these drugs are also available. See “Multiclass combination drugs” above.

You may hear NRTIs referred to as “nukes.” They work by interrupting the life cycle of HIV as it tries to copy itself. These drugs also have other actions that prevent HIV from replicating in the body. Examples of NRTIs include:

  • abacavir (Ziagen)
  • abacavir/lamivudine (Epzicom)
  • abacavir/lamivudine/zidovudine (Trizivir)
  • lamivudine/zidovudine (Combivir)
  • lamivudine (Epivir)
  • zidovudine (Retrovir)
  • emtricitabine/tenofovir disoproxil fumarate (Truvada)
  • emtricitabine (Emtriva)
  • tenofovir disoproxil fumarate (Viread)
  • emtricitabine/tenofovir alafenamide (Descovy)

Some NRTIs are rarely used and will be discontinued by the manufacturer by 2020. These drugs include:

  • didanosine (Videx)
  • didanosine extended-release (Videx EC)
  • stavudine (Zerit)

These drugs work in a similar way to NRTIs. They stop the virus from replicating itself in your body. Examples of these drugs include:

  • efavirenz (Sustiva)
  • etravirine (Intelence)
  • nevirapine (Viramune)
  • nevirapine extended-release (Viramune XR)
  • rilpivirine (Edurant)
  • delavirdine mesylate (Rescriptor): rarely used

Several combinations of these drugs are also available. See “Multiclass combination drugs” above.

Protease inhibitors work by binding to protease. This is a protein that HIV needs to replicate in the body. When protease can’t do its job, the virus can’t complete the process that makes new copies. This reduces the number of viruses that can infect more cells. Some protease inhibitors are only approved by the FDA to treat hepatitis C, but these are not the same as those used to treat HIV infection.

Examples of protease inhibitors used to treat HIV include:

  • atazanavir/cobicistat (Evotaz)
  • darunavir/cobicistat (Prezcobix)
  • lopinavir/ritonavir (Kaletra)
  • ritonavir (Norvir): always used to boost other medications, such as atazanavir, lopinavir, darunavir, or elvitegravir
  • atazanavir (Reyataz): often given together with ritonavir
  • darunavir (Prezista): must be given together with ritonavir
  • fosamprenavir (Lexiva): often given together with ritonavir
  • tipranavir (Aptivus): must be given together with ritonavir

HIV protease inhibitors that are rarely used because they have more side effects include:

  • nelfinavir (Viracept)
  • indinavir (Crixivan): often given together with ritonavir
  • saquinavir (Invirase): must be given together with ritonavir

Entry inhibitors are another class of HIV medication. HIV needs a host T-cell in order to make copies of itself. These drugs block the virus from entering a host T-cell. This prevents the virus from replicating itself.

Entry inhibitors are rarely used in the United States because other available drugs are more effective and better tolerated. An example of an entry inhibitor is:

  • enfuvirtide (Fuzeon)

CCR5 antagonists block HIV from entering cells. CCR5 antagonists are rarely used in the United States because other available drugs are more effective. An example of this type of drug includes:

  • maraviroc (Selzentry)

CYP3A are enzymes that protect liver and gastrointestinal health. CYP3A inhibitors increase the levels of certain HIV drugs in the body. These HIV drugs include protease inhibitors and certain integrase inhibitors. Examples of CYP3A inhibitors include:

  • cobicistat (Tybost)
  • ritonavir (Norvir)

Because HIV affects the immune system, researchers are studying ways that biological drugs can prevent viral replication. Certain immune-based treatments have been successful in some people in clinical trials and are currently being researched. They would be used along with other HIV medications.

An example of an immune-based therapy is ibalizumab. This drug is an entry inhibitor. It prevents HIV from entering certain immune cells.

Many HIV drugs can cause temporary side effects when first used. These effects can include:

  • diarrhea
  • dizziness
  • headaches
  • fatigue
  • fever
  • muscle aches
  • nausea
  • vomiting

You may have side effects for several weeks after starting a new medication. If these side effects get worse or last longer than a few weeks, talk to your doctor. Your doctor may suggest ways to ease your side effects, or they may prescribe you a different drug.

Less often, HIV drugs can cause serious or long-term side effects. These effects depend on the type of drugs you’re taking. Your doctor can tell you more.

There’s no cure for HIV yet, but prescription medications can help slow the progression of the virus. Drugs can also improve your symptoms and make living with HIV more comfortable. This medication list is a brief overview of the types of drugs that are available to treat HIV. Talk to your doctor about all of these options. With your help, your doctor can determine the best treatment plan for you.

The sentences quoted in this table are maximums only and are not reflective of sentences given in the majority of drug offences, for more guidance on this issue please go to our section on sentencing. Please note that not all controlled substances are listed in this table - a comprehensive list is available from the Home Office. Trafficking offences refer to all supply offences including conspiracy or attempt to supply; production offences and offences involving importation and exportation. Consult Release or a solicitor for information on substances not covered in the table.

Amphetamines (including dexamphetamine)

Amphetamines are class B, schedule 2 drugs. It is illegal to possess them without a prescription or to supply or produce them without a licence. If prepared for injection they become class A substances.

Possession of class B drugs carries a maximum sentence of 5 years’ imprisonment and a fine. Trafficking offences carry maximum sentences of 14 years’ imprisonment and a fine.

Possession of class A drugs carries a maximum sentence of 7 years’ imprisonment and/a fine. Trafficking offences carry a maximum sentence of life imprisonment and a fine.

Anabolic steroids

Anabolic steroids are class C, schedule 4(ii) drugs. Possession is lawful as long as the drug is for personal use. Anabolic steroids can also be imported or exported for personal use where a person physically carries out that importation or exportation.

Unauthorised supply or production is an offence and carries a maximum of 14 years’ imprisonment and a fine.

Benzodiazepines (including diazepam, flunitrazepam and temazepam)

Benzodiazepines are class C drugs. Some benzodiazepines belong to schedule 3 and some belong to schedule 4(1). Possession without a prescription, or supply or production without a licence, is illegal.

List Of Narcotics By Class

Possession carries a maximum sentence of 2 years’ imprisonment and a fine. Supply or production carries a maximum sentence of 14 years’ imprisonment and a fine.

Buprenorphine (including Subutex)

Buprenorphine is a class C, schedule 3 drug. Possession is illegal without prescription and carries a maximum sentence of 2 years’ imprisonment and a fine.

Illegal supply or production carries a maximum sentence of 14 years’ imprisonment and a fine.

BZP (and other piperazines)

Piperazines (including BZP and TFMPP) are Class C, Schedule 1 drugs. It is illegal to possess, supply or prescribe them.

Possession of Class C drugs carries a maximum sentence of 2 years’ imprisonment and a fine. Possession with intent to supply, trafficking offences and production of Class C drugs carry a maximum sentence of 14 years imprisonment and a fine.

Cannabis

Cannabis is a class B, schedule 1 drug. It is illegal to possess, supply or produce this drug. Special police guidelines exist in relation to arrest for possession of cannabis. (Cannabis was reclassified to a Class B drug in January 2009.)

Possession carries a maximum sentence of 5 years’ imprisonment and a fine. Trafficking offences carry a maximum sentence of 14 years’ imprisonment and a fine.

Policing Cannabis - guidelines on arrest

New guidelines were issued by the Association of Chief Police Officers (‘ACPO’) in response to the reclassification of cannabis to a Class B drug (published 28 January 2009). The guidelines advise police officers to take an 'escalating' approach to the policing of cannabis possession. It outlines three possible responses for officers to take where they believe they have found an individual in possession of cannabis for personal use:

Cannabis Warnings: A person found in possession of cannabis for the first time can receive a cannabis warning if there are no aggravating factors (please see below). Where a police officer decides to proceed with a cannabis warning the individual should be warned that:

  • a record of the investigation will be made at the police station;
  • the offence of possession will be recorded against them, for statistical purposes, as a detected crime;
  • this procedure does not constitute a criminal record.

Penalty Notice for Disorder (PND): Where someone has already received a cannabis warning and is again caught in possession, then the police have the discretion to issue an on the spot fine ('PND') for £80.00. If the PND is paid within 21 days no further action will be taken and no criminal record will exist. A PND can be challenged, and if challenged will result in criminal proceedings at the Magistrates Court. Failure to pay will result in a fine for the original penalty plus 50% (£120) being registered against the defendant at their local Magistrates’ Court. A person has a right to refuse a PND but this will probably result in arrest.

Arrest: An individual who has received a cannabis warning and a PND and is caught again for cannabis possession should be arrested and taken to the police station. At this point, and depending on the circumstances, either the matter will be dealt with by way of charge, caution or no further action (including the possibility of issuing a further cannabis warning or a PND).

If a person is caught in possession of cannabis and there is one or more aggravating condition present then they may be arrested. The following are considered to be aggravating conditions:

  • smoking in a public place;
  • where there is a locally identified policing problem;
  • if the person is aged 17 or under;
  • someone considered to be vulnerable;
  • if the individual is a repeat or persistent offender.

If caught in possession of a small amount of cannabis for personal use AND you have never received either a cannabis warning or a PND and where none of the aggravating conditions are present AND the police deal with the matter either by issuing a caution or charging, legal advice should be sought by contacting Release.

The above guidelines apply to adults only. Those aged 17 or under will be dealt with under the Final Warning Scheme i.e. they will receive either a reprimand or a warning or they may face prosecution. The guidelines do state that arrest is not necessary in all cases involving young people and where possible they should be taken home to their parents/ guardians - where this occurs action can be taken at a later date.

Cocaine (including crack cocaine)

Cocaine is a class A, schedule 2 drug. Possession without a prescription is illegal. It is illegal to supply or produce cocaine.

Possession carries a maximum sentence of 7 years’ imprisonment and a fine. Supply or production carries a maximum sentence of life imprisonment and a fine.

Codeine

Codeine is a class B, schedule 2 drug. If prepared for injection it becomes a class A substance. It is illegal to possess without prescription or to supply or produce without a licence.

Illegal possession carries a maximum sentence of 5 years’ imprisonment and a fine. Trafficking offences carry a maximum sentence of 14 years’ imprisonment and a fine.

Possession of class A drugs carries a maximum sentence of 7 years’ imprisonment and/a fine. Trafficking offences carry a maximum sentence of life imprisonment and a fine.

DMT

DMT (N,N-dimethyltryptamine) is a Class A, Schedule 1 drug. It is illegal to possess, supply or prescribe.

Possession of Class A drugs carries a maximum sentence of 7 years’ imprisonment and a fine. Possession with intent to supply, trafficking offences and production of Class A drugs carry a maximum sentence of life imprisonment and a fine.

Ecstasy

Ecstasy is a class A, schedule 1 drug. Possession, supply and production offences are illegal.

Possession carries a maximum sentence of 7 years’ imprisonment and/a fine. Trafficking offences carry a maximum sentence of life imprisonment and a fine.

GHB

GHB is a class C, schedule 4(1) drug. It is illegal to possess, supply or produce this drug.

Possession carries a maximum sentence of 2 years’ imprisonment and a fine. Trafficking offences carry a maximum sentence of 14 years’ imprisonment and a fine.

Hallucinogenic mushrooms containing psilocin

Any fungus which contains psilocin is a class A, schedule 1 drug.

Possession carries a maximum of 7 years imprisonment and/or fine. Supply of mushrooms carries a maximum of life imprisonment and/or fine.

No offence is committed if the fungus is growing naturally without being cultivated, and if it has not been picked.

Heroin (diamorphine)

Heroin is a class A, schedule 2 drug. It is illegal to possess without a prescription, or to supply or produce without a licence.

Possession carries a maximum sentence of 7 years’ imprisonment and a fine. Trafficking offences carry a maximum sentence of life imprisonment and a fine.

Khat

Khat is a class C, schedule 1 drug. It is illegal to possess, supply or produce this drug.

Possession carries a maximum sentence of 2 years’ imprisonment and a fine. Trafficking offences carry a maximum sentence of 14 years’ imprisonment and a fine.

Police officers will take a special 'escalating' approach to the policing of khat possession. There are three possible responses for officers to take where they believe they have found an individual in possession of khat for personal use:

Khat Warnings

A person found in possession of khat for the first time can receive a khat warning. Where a police officer decides to proceed with a khat warning the individual should be warned that:

  • a record of the investigation will be made at the police station;
  • the offence of possession will be recorded against them, for statistical purposes, as a detected crime;
  • this procedure does not constitute a criminal record.

Penalty Notice for Disorder (PND)

Where someone has already received a khat warning and is again caught in possession, then the police have the discretion to issue an on the spot fine ('PND') for £60.00. If the PND is paid within 21 days no further action will be taken and no criminal record will exist. A PND can be challenged, and if challenged will result in criminal proceedings at the Magistrates Court. Failure to pay will result in a fine for the original penalty plus 50% (£90) being registered against the defendant at their local Magistrates’ Court. A person has a right to refuse a PND but this will probably result in arrest.

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Arrest

An individual who has received a khat warning and a PND and is caught again for khat possession should be arrested and taken to the police station. At this point, and depending on the circumstances, either the matter will be dealt with by way of charge, caution or no further action (including the possibility of issuing a further cannabis warning or a PND).

Ketamine

Ketamine is a class B, schedule 4(1) drug. It is illegal to possess, supply or produce this drug.

Possession carries a maximum sentence of 5 years’ imprisonment and/or fine. Trafficking offences carry a maximum sentence of 14 years’ imprisonment and a fine.

LSD

LSD is a class A, schedule 1 drug. Possession, supply and production of LSD are offences.

Possession carries a maximum sentence of 7 years’ imprisonment and a fine. Trafficking offences carry a maximum sentence of life imprisonment and a fine.

Mephedrone

Mephedrone is a class B drug. It is illegal to possess, supply or produce this drug.

Possession of the drug could result in up to 5 years' imprisonment and a fine, supply offences in up to 14 years' imprisonment and a fine.

Methadone

Methadone is a class A, schedule 2 drug. It is illegal to possess without a prescription, or to supply or produce without a licence.

Possession carries a maximum sentence of 7 years’ imprisonment and a fine. Trafficking offences carry a maximum sentence of life imprisonment and a fine.

Methoxetamine

Methoxetamine is a Class B, Schedule 1 drug. It is illegal to possess, supply or produce.

Possession of Class B drugs carry a maximum sentence of 5 years’ imprisonment and a fine. Possession with intent to supply, trafficking offences and production of Class B drugs carry a maximum sentence of 14 year’s imprisonment and a fine.

Methylamphetamine

This is a class A, schedule 2 drug. It is an offence to possess, supply or produce.

Possession carries a maximum sentence of 7 years’ imprisonment and/or fine. Trafficking offences carry a maximum sentence of life imprisonment and a fine.

Methylone

Methylone is a class B drug. It is illegal to possess, supply or produce this drug.

Possession of the drug could result in up to 5 years' imprisonment, supply offences in up to 14 years' imprisonment.

Morphine

Morphine is a class A, schedule 2 drug. It is illegal to possess without a prescription, or to supply or produce without a licence.

Possession carries a maximum sentence of 7 years’ imprisonment and a fine. Trafficking offences carry a maximum sentence of life imprisonment and a fine.

NRG-1, NRG-3, Naphyrone

Naphyrone (and the related drugs NRG-1 and NRG-3) is a Class B, Schedule 1 drug. It is illegal to possess, supply or produce.

Possession of Class B drugs carry a maximum sentence of 5 years’ imprisonment and a fine. Possession with intent to supply, trafficking offences and production of Class B drugs carry a maximum sentence of 14 year’s imprisonment and a fine.

Novel Psychoactive Substances (Legal Highs)

Please see our guide on the Psychoactive Substances Act 2016.

Opium

This is a class A drug. In its raw form it is a schedule 1 drug but in a medicinal form it is schedule 2. It is an offence to possess, supply or produce.

Possession carries a maximum sentence of 7 years’ imprisonment and/a fine. Trafficking offences carry a maximum sentence of life imprisonment and a fine.

PMMA/PMA

Para-methoxyamphetamine (PMA) and para-methoxymethamphetamine (PMMA) are Class A, Schedule 1 drugs. They are illegal to possess, supply or produce.

Possession of Class A drugs carries a maximum sentence of 7 years’ imprisonment and a fine. Possession with intent to supply, trafficking offences and production of Class A drugs carry a maximum sentence of life imprisonment and a fine.

Subutex

Subutex is a Class C, Schedule 3 drug. It is illegal to possess, supply or produce it.

Possession of Class C drugs carries a maximum sentence of 2 years’ imprisonment and a fine. Possession with intent to supply, trafficking offences and production of Class C drugs carry a maximum sentence of 14 years imprisonment and a fine.

Solvents & gases

Please see our guide on the Psychoactive Substances Act 2016 which is now the legislation that deals with solvents and gases.

Synthetic Cannabinoids (including Spice and K2)

The law around synthetic cannabinoids is complicated. Some substances belonging to this group are controlled as Class B Schedule 1 substances and as such it is illegal to possess, supply or produce.

Possession of Class B drugs carry a maximum sentence of 5 years’ imprisonment and a fine. Possession with intent to supply, trafficking offences and production of Class B drugs carry a maximum sentence of 14 year’s imprisonment and a fine.

Not all synthetic cannabinoids are controlled under the Misuse of Drugs Act 1971. Producers of this group of drugs have altered the chemical structure so that newer products on the market fall out of the scope of the legislation. In order to address this situation the UK Government passed the Psychoactive Substances Act 2016. This new legislation, which came into force on 26 May 2016, creates the following offences in relation to new psychoactive substances: importation including for personal use; exportation; supply; and production. The maximum sentence for these activities is seven years in prison. Possession is not an offence under the legislation but possession in a custodial setting, e.g. prison, is an offence attracting a maximum of two years imprisonment. Please see our guide on the Psychoactive Substances Act 2016 for a more detailed analysis of the law.

2C-B (& other 2C-type drugs)

2C drugs (including 2C-B) are Class A, Schedule 1 drugs. They are illegal to possess, supply and produce.

Possession of Class A drugs carries a maximum sentence of 7 years’ imprisonment and a fine. Possession with intent to supply, trafficking offences and production of Class A drugs carry a maximum sentence of life imprisonment and a fine.

5-MeO Group

5-MeO-DMT (not to be confused with DMT) is a Class A, Schedule 1 drug. It is illegal to possess, supply and produce.

List Of Narcotics By Class

Possession of Class A drugs carries a maximum sentence of 7 years’ imprisonment and a fine. Possession with intent to supply, trafficking offences and production of Class A drugs carry a maximum sentence of life imprisonment and a fine.

List Of Narcotics By Strength

The remaining drugs that fall within the 5-MeO group are not controlled under the Misuse of Drugs ACT 1971. They fall within the category of 'new psychoactive substances' ('NPS'). In order to address the issue of NPS the UK Government passed the Psychoactive Substances Act 2016. This new legislation, which came into force on 26 May 2016, creates the following offences in relation to NPS: importation including for personal use; exportation; supply; and production. The maximum sentence for these activities is seven years in prison. Possession is not an offence under the legislation but possession in a custodial setting, e.g. prison, is an offence attracting a maximum of two years imprisonment. Please see our guide on the Psychoactive Substances Act 2016 for a more detailed analysis of the law.